306 at Nisibis, Mesopotamia (in modern Syria)
9 June 373 at Edessa (in modern Iraq)
Spiritual directors and spiritual leaders
The aforesaid facts represent all that is historically certain concerning the career of Ephraem. All details added later by Syrian biographers are at best of doubtful value. To this class belong not only the legendary and occasionally puerile traits so dear to Oriental writers, but also others seemingly reliable, e.g. an alleged journey to Egypt with a sojourn of eight years, during which he is said to have confuted publicly certain spokesmen of the Arian heretics. The relations of St. Ephraem and St. Basil are narrated by very reliable authors, e.g. St. Gregory of Nyssa (the Pseudo?) and Sozomen, according to whom the hermit of Edessa, attracted by the great reputation of St. Basil, resolved to visit him at Caesarea. He was warmly received and was ordained deacon by St. Basil; four years later he refused both the priesthood and the episcopate that St. Basil offered him through delegates sent for that purpose to Edessa. Though Ephraem seems to have been quite ignorant of Greek, this meeting with St. Basil is not improbable; some good critics, however, hold the evidence insufficient, and therefore reject it, or at least withhold their adhesion. The life of St. Ephraem, therefore, offers not a few obscure problems; only the general outline of his career is known to us. It is certain, however, that while he lived he was very influential among the Syrian Christians of Edessa, and that his memory was revered by all, Orthodox, Monophysites, and Nestorians. They call him the "sun of the Syrians," the "column of the Church", the "harp of the Holy Spirit". More extraordinary still is the homage paid by the Greeks who rarely mention Syrian writers. Among the works of St. Gregory of Nyssa (P.G., XLVI, 819) is a sermon (though not acknowledged by some) which is a real panegyric of St. Ephraem. Twenty years after the latter's death St. Jerome mentions him as follows in his catalogue of illustrious Christians: "Ephraem, deacon of the Church of Edessa, wrote many works [opuscula] in Syriac, and became so famous that his writings are publicly read in some churches after the Sacred Scriptures. I have read in Greek a volume of his on the Holy Spirit; though it was only a translation, I recognized therein the sublime genius of the man" (De viris illustr., c. cxv). Theodoret of Cyrus also praised his poetic genius and theological knowledge (Hist. Eccl., IV, xxvi). Sozomen pretends that Ephraem wrote 3,000,000 verses, and gives the names of some of his disciples, some of whom remained orthodox, while others fell into heresy (Hist. Eccl., III, xvi). From the Syrian and Byzantine Churches the fame of Ephraem spread among all Christians. The Roman Martyrology mentions him on 1 February. In their menologies and synaxaria Greeks and Russians, Jacobites, Chaldeans, Copts, and Armenians honour the holy deacon of Edessa.
(Taken from Catholic Encyclopedia